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Vitiligo | Vitiligo Pictures | Nodular Prostatic Hyperplasia | Tubular Adenoma | Tubular Adenoma of Colon | Vitiligo Michael Jackson

Vitiligo is a chronic disorder that causes depigmentation in patches of skin. It occurs when the melanocytes, the cells responsible for skin pigmentation which are derived from the neural crest, die or are unable to function.

The precise pathogenesis, or cause, of vitiligo is complex and not yet fully understood.

There is some evidence suggesting it is caused by a combination of autoimmune, genetic, and environmental factors. It is also common in people with thyroid disorders. The population incidence worldwide is considered to be less than 1 percent. Non-segmental vitiligo has a greater prevalence than the disorder’s other form(s).

The most notable symptom of vitiligo is depigmentation of patches of skin that occurs on the extremities. Although patches are initially small, they often enlarge and change shape. When skin lesions occur, they are most prominent on the face, hands and wrists.

There is no cure for vitiligo but there are a number of treatments available which can slow down or improve the condition. In fair-skinned people, avoiding tanning of normal skin can make patches of vitiligo much less noticeable. Treatment options generally fall into four groups.

Sunblock and other means to protect the pale skin

A high protection sun-block (factor 20 or above) is applied to areas of vitiligo to prevent sunburn. Affected areas of skin are protected when the sun is strong, especially in the middle of the day by wearing, for example, a wide brimmed hat and long sleeved clothing.

Skin camoflague

In mild cases, vitiligo patches can be hidden with makeup or other cosmetic camouflage solutions. If the affected person is pale-skinned, the patches can be made less visible by avoiding sunlight and the sun tanning of unaffected skin. However, exposure to sunlight may also cause the melanocytes to regenerate to allow the pigmentation to come back to its original color.

Treatments that aim to reverse the changes in the skin

The traditional treatment used by dermatologists is the application ofcorticosteroid cream.

Studies have also shown that immunomodulator creams such as Protopic and Elidel also cause repigmentation in some cases, when used with UVB narrowband treatments.

Treatment to completely de-pigment the skin

In cases of extensive vitiligo the option to de-pigment the unaffected skin may be considered to render the skin an even colour. The removal of all the skin pigment is permanent and it takes about a year to complete.

Tags:Nodular Prostatic Hyperplasia, Tubular Adenoma, Tubular Adenoma of Colon, Vitiligo, Vitiligo Michael Jackson, Vitiligo Pictures

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